Bacteriophage Publications - Intralytix, Inc.

safety by nature depiction

safety by nature depiction

intralytx bacteriophage and Technology

intralytx bacteriophage and Food Safety

intralytx bacteriophage and Environmental Sanitation

Environmental Sanitation

intralytx bacteriophage and Veterinary Applications

Veterinary Applications

intralytx bacteriophage and Human Therapeutics

Human Therapeutics

intralytx bacteriophage and Probiotics

Publications

Keywords

Targets

Salmonella

Escherichia coli

STEC

Listeria

Shigella

Food Categories

produce

pet food

poultry

meat

fish

dairy

Food Products

broccoli

cantaloupe

strawberries

pet food

ground turkey

chicken

meat

raw

fillet

cucumber

pork

mung bean

sprouts

seeds

apples

lettuce

tomato

spinach

beef

steak

leafy

greens

chuck

roast

salmon

cheese

melon

ham

smoked

yogurt

leaf

Safety and Tolerability of ShigActive™, a Shigella spp. Targeting Bacteriophage Preparation, in a Phase 1 Randomized, Double-Blind, Controlled Clinical Trial

Wilbur H. Chen, Joelle Woolston, Silvia Grant-Beurmann, Courtney K. Robinson, Garima Bansal, Joseph Nkeze, Jasnehta Permala-Booth, Claire M. Fraser, Sharon M. Tennant, Mallory C. Shriver, Marcela F. Pasetti, Yuanyuan Liang, Karen L. Kotloff, Alexander Sulakvelidze, and Jennifer A. Schwartz

A Bacteriophage Cocktail Targeting Yersinia pestis Provides Strong Post-Exposure Protection in a Rat Pneumonic Plague Model

Paul B. Kilgore, Jian Sha, Emily K. Hendrix, Blake H. Neil, William S. Lawrence, Jennifer E. Peel, Lauren Hittle, Joelle Woolston, Alexander Sulakvelidze, Jennifer A. Schwartz, Ashok K. Chopra.

A Bacteriophage Cocktail Significantly Reduces Listeria monocytogenes without Deleterious Impact on the Commensal Gut Microbiota under Simulated Gastrointestinal Conditions

Jakobsen RR, Trinh JT, Bomholtz L, Brok-Lauridsen SK, Sulakvelidze A, Nielsen DS.

Evaluation of a Preharvest Bacteriophage Therapy for Control of Salmonella within Bovine Peripheral Lymph Nodes

Wottlin LR, Edrington TS, Brown TR, Zook CA, Sulakvelidze A, Droleskey R, Genovese KJ, Nisbet DJ.

Bacteriophages against Vibrio coralliilyticus and Vibrio tubiashii: Isolation, Characterization, and Remediation of Larval Oyster Mortalities

Richards GP, Watson MA, Madison D, Soffer N, Needleman DS, Soroka DS, Uknalis J, Baranzoni GM, Church KM, Polson SW, Elston R, Langdon C, Sulakvelidze A.

Phage Biocontrol Applications in Food Production and Processing

Amit Vikram, Joelle Woolston and Alexander Sulakvelidze

Phage biocontrol improves food safety by significantly reducing both the concentration and occurrence of Escherichia coli O157:H7 in various foods

Vikram, A., Tokman, J., Woolston, J., and Sulakvelidze, A.

Treatment of fresh produce with a Salmonella-targeted bacteriophage cocktail is compatible with chlorine or peracetic acid and more consistently preserves the microbial community on produce.

Moye Z, Rajanna C, Tokman J, Fanelli B, Hasan N, Marek P, Senecal A, Sulakvelidze A.

Employing list-shield bacteriophage as a bio-control intervention for Listeria monocytogenes from raw beef surface and maintain meat quality during refrigeration storage

Ishaq, A., P. D. Ebner, Q. A. Syed, and H. Ubaid ur Rahman.

SalmoFresh™ effectiveness in controlling Salmonella on romaine lettuce, mung bean sprouts and seeds.

Zhang, X., Niu, Y.D., Nan, Y., Stanford, K., Holley, R., McAllister, T., and Narváez-Bravo, C.

A Bacteriophage Cocktail Eliminates Salmonella Typhimurium from the Human Colonic Microbiome while Preserving Cytokine Signaling and Preventing Attachment to and Invasion of Human Cells by Salmonella In Vitro

Moye ZD, Woolston J, Abbeele PVD, Duysburgh C, Verstrepen L, Das CR, Marzorati M, Sulakvelidze A.

Survival of Salmonella Newport on Whole and Fresh-Cut Cucumbers Treated with Lytic Bacteriophages.

Sharma, M., Dashiell, G., Handy, E.T., East, C., Reynnells, R., White, C., Nyarko, E., Micallef, S., Hashem, F., and Millner, P.D.

Reduction of Listeria monocytogenes on chicken breasts by combined treatment with UV-C light and bacteriophage ListShield.

Yang, S., Sadekuzzaman, M., and Ha, S.-D.

Applicability of commercial phage-based products against Listeria monocytogenes for improvement of food safety in Spanish dry-cured ham and food contact surfaces.

Gutiérrez, D., Rodríguez-Rubio, L., Fernández, L., Martínez, B., Rodríguez, A., and García, P.

Bacteriophage preparation lytic for Shigella significantly reduces Shigella sonnei contamination in various foods.

Soffer N, Woolston J, Li M, Das C, Sulakvelidze A.

Effectiveness of a phage cocktail as a biocontrol agent against L. monocytogenes biofilms.

Sadekuzzaman, M., S. Yang, M. F. R. Mizan, H.-S. Kim, and S.-D. Ha.

Effects of Salmonella bacteriophage, nisin and potassium sorbate and their combination on safety and shelf life of fresh chilled pork.

Wang, C., Yang, J., Zhu, X., Lu, Y., Xue, Y., and Lu, Z.

Bacteriophages safely reduce Salmonella contamination in pet food and raw pet food ingredients.

Soffer, N., Abuladze, T., Woolston, J., Li, M., Hanna, L.F., Heyse, S., Charbonneau, D., and Sulakvelidze, A.

Reduction of Salmonella on chicken breast fillets stored under aerobic or modified atmosphere packaging by the application of lytic bacteriophage preparation SalmoFresh™

Sukumaran, A.T., Nannapaneni, R., Kiess, A., and Sharma, C.S.

Bacteriophage administration significantly reduces Shigella colonization and shedding by Shigella-challenged mice without deleterious side effects and distortions in the gut microbiota

Mai V, Ukhanova M, Reinhard MK, Li M, Sulakvelidze A.

Bacteriophage Cocktail for Biocontrol of Salmonella in Dried Pet Food.

Heyse, S., Hanna, L.F., Woolston, J., Sulakvelidze, A., and Charbonneau, D.

Bacteriophage cocktail significantly reduces or eliminates Listeria monocytogenes contamination on lettuce, apples, cheese, smoked salmon and frozen foods

Perera, M., Abuladze, T., Li M., Woolston, J., and Sulakvelidze, A.

Reduction of Salmonella on chicken meat and chicken skin by combined or sequential application of lytic bacteriophage with chemical antimicrobials.

Sukumaran, A.T., Nannapaneni, R., Kiess, A., and Sharma, C.S.

Efficacy of Lytic Bacteriophage Preparation in Reducing Salmonella In Vitro, on Turkey Breast Cutlets, and on Ground Turkey.

Sharma, C.S., Dhakal, J., and Nannapaneni, R.

Additive Approach for Inactivation of Escherichia coli O157:H7, Salmonella, and Shigella spp. on Contaminated Fresh Fruits and Vegetables Using Bacteriophage Cocktail and Produce Wash.

Magnone, J.P., Marek, P.J., Sulakvelidze, A., and Senecal, A.G.

Lytic bacteriophages reduce Escherichia coli O157:H7 on fresh cut lettuce introduced through cross-contamination.

Ferguson, S., Roberts, C., Handy, E., and Sharma, M.

Additive Approach for Inactivation of Escherichia coli O157:H7, Salmonella, and Shigella spp. on Contaminated Fresh Fruits and Vegetables Using Bacteriophage Cocktail and Produce Wash.

Magnone, J.P., Marek, P.J., Sulakvelidze, A., and Senecal, A.G.

Biocontrol of Escherichia coli O157:H7 on fresh-cut leafy greens.

Boyacioglu, O., Sharma, M., Sulakvelidze, A., and Goktepe, I.

Additive Approach for Inactivation of Escherichia coli O157:H7, Salmonella, and Shigella spp. on Contaminated Fresh Fruits and Vegetables Using Bacteriophage Cocktail and Produce Wash.

Magnone, J.P., Marek, P.J., Sulakvelidze, A., and Senecal, A.G.

Bacteriophage cocktail significantly reduces Escherichia coli O157:H7 contamination of lettuce and beef, but does not protect against recontamination.

Carter, C.D., Parks, A., Abuladze, T., Li, M., Woolston, J., Magnone, J., Senecal, A., Kropinski, A.M., and Sulakvelidze, A.

Bacteriophage cocktail significantly reduces Escherichia coli O157:H7 contamination of lettuce and beef, but does not protect against recontamination.

Carter, C.D., Parks, A., Abuladze, T., Li, M., Woolston, J., Magnone, J., Senecal, A., Kropinski, A.M., and Sulakvelidze, A.

Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected Mice.

Mai, V., Ukhanova, M., Visone, L., Abuladze, T., and Sulakvelidze, A.

Effectiveness of bacteriophages in reducing Escherichia coli O157:H7 on fresh-cut cantaloupes and lettuce.

Sharma, M., Patel, J.R., Conway, W.S., Ferguson, S., and Sulakvelidze, A.

Bacteriophages reduce experimental contamination of hard surfaces, tomato, spinach, broccoli, and ground beef by Escherichia coli O157:H7

Abuladze, T., Li, M., Menetrez, M.Y., Dean, T., Senecal, A., and Sulakvelidze, A.

Bacteriophages reduce experimental contamination of hard surfaces, tomato, spinach, broccoli, and ground beef by Escherichia coli O157:H7

Abuladze, T., Li, M., Menetrez, M.Y., Dean, T., Senecal, A., and Sulakvelidze, A.

Optimizing Concentration and Timing of a Phage Spray Application To Reduce Listeria monocytogenes on Honeydew Melon Tissue.

Leverentz, B., Conway, W.S., Janisiewicz, W., and Camp, M.J.

Biocontrol of Listeria monocytogenes on Fresh-Cut Produce by Treatment with Lytic Bacteriophages and a Bacteriocin.

Leverentz, B., Conway, W.S., Camp, M.J., Janisiewicz, W.J., Abuladze, T., Yang, M., Saftner, R., and Sulakvelidze, A.