Scientific Literature
 

Targets
Salmonella, Escherichia coli (STEC), Listeria, Shigella

Food Categories
produce, pet food, poultry, meat, fish, dairy

Food Products
broccoli, cantaloupe, strawberries, pet food, ground turkey, chicken, meat, raw, fillet, cucumber, pork, mung bean, sprouts, seeds, Gala apples, romaine lettuce, tomato, spinach, beef, steak, leafy, greens, chuck, roast, salmon, cheese, melon, dry-cured ham, smoked, yogurt, honeydew melon, leaf

Treatment of fresh produce with a Salmonella-targeted bacteriophage cocktail is compatible with chlorine or peracetic acid and more consistently preserves the microbial community on produce.
Journal of Food Safety, 2020
Moye Z, Rajanna C, Tokman J, Fanelli B, Hasan N, Marek P, Senecal A, Sulakvelidze A.

Phage biocontrol improves food safety by significantly reducing both the concentration and occurrence of Escherichia coli O157:H7 in various foods
Journal of Food Protection, 2020
Vikram, A., Tokman, J., Woolston, J., and Sulakvelidze, A.

SalmoFresh™ effectiveness in controlling Salmonella on romaine lettuce, mung bean sprouts and seeds.
International Journal of Food Microbiology, 2019
Zhang, X., Niu, Y.D., Nan, Y., Stanford, K., Holley, R., McAllister, T., and Narváez-Bravo, C.

A Bacteriophage Cocktail Eliminates Salmonella Typhimurium from the Human Colonic Microbiome while Preserving Cytokine Signaling and Preventing Attachment to and Invasion of Human Cells by Salmonella In Vitro
Journal of Food Protection, 2019
Moye ZD, Woolston J, Abbeele PVD, Duysburgh C, Verstrepen L, Das CR, Marzorati M, Sulakvelidze A.

Survival of Salmonella Newport on Whole and Fresh-Cut Cucumbers Treated with Lytic Bacteriophages.
Journal of Food Protection, 2017
Sharma, M., Dashiell, G., Handy, E.T., East, C., Reynnells, R., White, C., Nyarko, E., Micallef, S., Hashem, F., and Millner, P.D.

Effects of Salmonella bacteriophage, nisin and potassium sorbate and their combination on safety and shelf life of fresh chilled pork.
Food Control, 2017
Wang, C., Yang, J., Zhu, X., Lu, Y., Xue, Y., and Lu, Z.

Reduction of Listeria monocytogenes on chicken breasts by combined treatment with UV-C light and bacteriophage ListShield.
LWT, 2017
Yang, S., Sadekuzzaman, M., and Ha, S.-D.

Applicability of commercial phage-based products against Listeria monocytogenes for improvement of food safety in Spanish dry-cured ham and food contact surfaces.
Food Control, 2017
Gutiérrez, D., Rodríguez-Rubio, L., Fernández, L., Martínez, B., Rodríguez, A., and García, P.

Bacteriophage preparation lytic for Shigella significantly reduces Shigella sonnei contamination in various foods.
PLoS One , 2017
Soffer N, Woolston J, Li M, Das C, Sulakvelidze A.

Bacteriophages safely reduce Salmonella contamination in pet food and raw pet food ingredients.
Bacteriophage, 2016
Soffer, N., Abuladze, T., Woolston, J., Li, M., Hanna, L.F., Heyse, S., Charbonneau, D., and Sulakvelidze, A.

Reduction of Salmonella on chicken breast fillets stored under aerobic or modified atmosphere packaging by the application of lytic bacteriophage preparation SalmoFresh™
Poultry Science, 2016
Sukumaran, A.T., Nannapaneni, R., Kiess, A., and Sharma, C.S.

Bacteriophage Cocktail for Biocontrol of Salmonella in Dried Pet Food.
Journal of Food Protection, 2015
Heyse, S., Hanna, L.F., Woolston, J., Sulakvelidze, A., and Charbonneau, D.

Efficacy of Lytic Bacteriophage Preparation in Reducing Salmonella In Vitro, on Turkey Breast Cutlets, and on Ground Turkey.
Journal of Food Protection, 2015
Sharma, C.S., Dhakal, J., and Nannapaneni, R.

Reduction of Salmonella on chicken meat and chicken skin by combined or sequential application of lytic bacteriophage with chemical antimicrobials.
International Journal of Food Microbiology, 2015
Sukumaran, A.T., Nannapaneni, R., Kiess, A., and Sharma, C.S.

Bacteriophage cocktail significantly reduces or eliminates Listeria monocytogenes contamination on lettuce, apples, cheese, smoked salmon and frozen foods
Food Microbiology, 2015
Perera, M., Abuladze, T., Li M., Woolston, J., and Sulakvelidze, A.

Bacteriophage administration significantly reduces Shigella colonization and shedding by Shigella-challenged mice without deleterious side effects and distortions in the gut microbiota
Bacteriophage, 2015
Mai V, Ukhanova M, Reinhard MK, Li M, Sulakvelidze A.

Additive Approach for Inactivation of Escherichia coli O157:H7, Salmonella, and Shigella spp. on Contaminated Fresh Fruits and Vegetables Using Bacteriophage Cocktail and Produce Wash.
Journal of Food Protection, 2013
Magnone, J.P., Marek, P.J., Sulakvelidze, A., and Senecal, A.G.

Biocontrol of Escherichia coli O157:H7 on fresh-cut leafy greens.
Bacteriophage, 2013
Boyacioglu, O., Sharma, M., Sulakvelidze, A., and Goktepe, I.

Lytic bacteriophages reduce Escherichia coli O157:H7 on fresh cut lettuce introduced through cross-contamination.
Bacteriophage, 2013
Ferguson, S., Roberts, C., Handy, E., and Sharma, M.

Additive Approach for Inactivation of Escherichia coli O157:H7, Salmonella, and Shigella spp. on Contaminated Fresh Fruits and Vegetables Using Bacteriophage Cocktail and Produce Wash.
Journal of Food Protection, 2013
Magnone, J.P., Marek, P.J., Sulakvelidze, A., and Senecal, A.G.

Additive Approach for Inactivation of Escherichia coli O157:H7, Salmonella, and Shigella spp. on Contaminated Fresh Fruits and Vegetables Using Bacteriophage Cocktail and Produce Wash.
Journal of Food Protection, 2013
Magnone, J.P., Marek, P.J., Sulakvelidze, A., and Senecal, A.G.

Bacteriophage cocktail significantly reduces Escherichia coli O157:H7 contamination of lettuce and beef, but does not protect against recontamination.
Bacteriophage, 2012
Carter, C.D., Parks, A., Abuladze, T., Li, M., Woolston, J., Magnone, J., Senecal, A., Kropinski, A.M., and Sulakvelidze, A.

Bacteriophage cocktail significantly reduces Escherichia coli O157:H7 contamination of lettuce and beef, but does not protect against recontamination.
Bacteriophage, 2012
Carter, C.D., Parks, A., Abuladze, T., Li, M., Woolston, J., Magnone, J., Senecal, A., Kropinski, A.M., and Sulakvelidze, A.

Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected Mice.
International Journal of Microbiology , 2010
Mai, V., Ukhanova, M., Visone, L., Abuladze, T., and Sulakvelidze, A.

Effectiveness of bacteriophages in reducing Escherichia coli O157:H7 on fresh-cut cantaloupes and lettuce.
Journal of Food Protection, 2009
Sharma, M., Patel, J.R., Conway, W.S., Ferguson, S., and Sulakvelidze, A.

Bacteriophages reduce experimental contamination of hard surfaces, tomato, spinach, broccoli, and ground beef by Escherichia coli O157:H7
Applied and Environmental Microbiology, 2008
Abuladze, T., Li, M., Menetrez, M.Y., Dean, T., Senecal, A., and Sulakvelidze, A.

Bacteriophages reduce experimental contamination of hard surfaces, tomato, spinach, broccoli, and ground beef by Escherichia coli O157:H7
Applied and Environmental Microbiology, 2008
Abuladze, T., Li, M., Menetrez, M.Y., Dean, T., Senecal, A., and Sulakvelidze, A.

Optimizing Concentration and Timing of a Phage Spray Application To Reduce Listeria monocytogenes on Honeydew Melon Tissue.
Journal of Food Protection, 2004
Leverentz, B., Conway, W.S., Janisiewicz, W., and Camp, M.J.

Biocontrol of Listeria monocytogenes on Fresh-Cut Produce by Treatment with Lytic Bacteriophages and a Bacteriocin.
Applied and Environmental Microbiology, 2003
Leverentz, B., Conway, W.S., Camp, M.J., Janisiewicz, W.J., Abuladze, T., Yang, M., Saftner, R., and Sulakvelidze, A.



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